Breakthrough in PCI

Protected PCI with Impella 2.5 reduces adverse events, with a 29% reduction in MACCE at 90 days

A Protected PCI is an Impella-supported procedure that maintains a patient’s hemodynamic stability, allowing you to do a more complete revascularization in a single session.

The Impella 2.5 is a temporary (≤ 6 hours) ventricular support device indicated for use during:

1-High risk PCI performed in urgent or

 2-Elective hemodynamically stable patients with severe coronary artery disease and 3-Depressed left ventricular ejection fraction, when a heart team, including a cardiac surgeon, has determined high risk PCI is the appropriate therapeutic option. Use of the Impella 2.5 in these patients may prevent hemodynamic instability that may occur during planned temporary coronary occlusions and may reduce peri- and post-procedural adverse events.

Impella is the only hemodynamic support device proven safe and effective at reducing adverse events in elective and urgent high risk PCI patients

The FDA indication for high risk PCI is defined as the combination of complex coronary artery disease (3VD or ULM), hemodynamic compromise (LVEF <=35%) and patient comorbidities.

Keynotes:

Safe & effective therapy1

Protected PCI with Impella 2.5 reduces adverse events, with a 29% reduction in MACCE at 90 days

Better quality of life2

58% reduction in heart failure classification NYHA Class III & Class IV

Patients go home faster3

2 days less time in the hospital

52% reduction in readmissions to the hospital for repeat procedures

MACCE: Major Adverse Cardiac and Cerebrovascular Event