Monday, July 9, 2012

Nicorandil Sustained Release Formulation

The present investigation revealed that Tamarindus kernals mucilage and guar gum, Ethyl cellulose and
HPMC appears to be suitable for use as a release retarding agents in the formulation of sustained release
matrix tablets because of its good swelling, good flow and suitability for matrix formulation.

From the dissolution study, it was concluded that Tamarindus kernals mucilage can be used as an excipient for
making sustained release matrix tablets of Nicorandil.

Nicorandil Sustained Release Formulation